"Dream, Dream, Dream! Conduct these dreams into thoughts, and then transform them into action."
- Dr. A. P. J. Abdul Kalam
28 Apr 2023
A method of preventing hair from going gray may have been discovered by a team of researchers. The tell-tale sign of aging—gray hair—is something that many women and men have tried to hide for generations. Now, researchers have found that certain stem cells have a unique ability to move within hair follicles, which could maintain the original pigment in the strands.
They found that as our hair ages, sheds, and repeatedly grows back, more of these stem cells become stuck in a compartment called the hair follicle bulge. They remain here and fail to travel back to their original location in the compartment, where proteins would have helped them regenerate into pigment cells—thus helping hairs keep their color.
The study, led by researchers at the NYU Grossman School of Medicine, observed the physically-aged hairs of mice and found that more and more stem cells became stuck when aging. These cells were also found to remain incapable of regenerating or maturing into pigment-producing hairs that keep their color.
By studying mice, the researchers were able to identify a molecule that can activate the Wnt signaling pathway and restore hair pigmentation. The molecule, called K(D)PT, was found to be effective in preventing gray hair in mice, suggesting that it may be a potential treatment for humans as well.
While the study is still in its early stages, the findings offer hope for those who are concerned about gray hair or hair loss. The researchers believe that the discovery of this protein and its role in hair pigmentation could lead to new treatments for a range of hair-related conditions.
The study has been met with excitement and interest from the scientific community, with many experts calling it a significant breakthrough in the field of hair research. While more research is needed to fully understand the role of the Wnt signaling pathway in hair pigmentation, the discovery of this protein could pave the way for new treatments and therapies to prevent or reverse gray hair.